Table 1.
Donor demographics
| Airway fibroblasts | Parenchymal fibroblasts | ||||||
|---|---|---|---|---|---|---|---|
| Non-COPD | COPD | Non-COPD vs COPD p value | Non-COPD | COPD | Non-COPD vs COPD p value | Airway vs parenchymal COPD p value | |
| N | 8 | 7 | 17 | 29 | |||
| Gender (M/F) | 2/6 | 6/1 | 0.0187 | 9/8 | 18/11 | 0.544 | 0.2336 |
| Age Mean (SD) |
63.36 (10.06) | 68 (5.63) | 0.3097 | 65.06 (11.31) | 65.1 (9.60) | 0.9994 | 0.4489 |
| Pack-years Mean (SD) |
21.6 (18.89) | 53.4 (29.84) | 0.0221 | 31.8 (25.52) | 39.8 (19.94) | 0.3345 | 0.1798 |
| FEV1% Mean (SD) |
100.8 (11) | 69.7 (18.5) | 0.0046 | 95.6 (17.2) | 47.8 (26.3) | < 0.0001 | 0.0457 |
| FEV1/FVC % Mean (SD) |
77.42 (7.2) | 59.8 (12) | 0.0035 | 76.6 (6.4) | 44.8 (15.5) | < 0.0001 | 0.0182 |
| GOLD stage | NA | 2× GS1, 3× GS2, 2× GS3 | NA | NA | 3× GS1, 10× GS2, 3× GS3, 13× GS4 | NA | NA |
M male, F female, COPD chronic obstructive pulmonary disease, SD standard deviation, FEV forced expiratory volume, FVC forced vital capacity, NA not applicable