Table 2.
Clinical outcomes of immunocompromised patients with RSV infection
| Variable, Number; (%) unless indicated otherwise | Children (N = 64) | Adult (N = 175) | p value | Total (N = 239) |
|---|---|---|---|---|
| All-cause admission to hospital (adults: 5 missing values) |
48 (75.0) | 107 (62.9) | 0.090 | 155 (66.2) |
| ARTI-attributable hospital admissiona (adults: 5 missing values) |
31 (48.4) | 58 (34.1) | 0.050 | 89 (38.0) |
| • Length of hospital stay (d) mean (SD)a | • 5 (3.5) | • 9 (12.0) | • < 0.001 | • 7 (9.0) |
| • Admission to the ICUa | • 2 (6.5) | • 17 (29.3) | • 0.014 | • 19 (21.3) |
| • Use of mechanical ventilationa | • 1 (3.2) | • 13 (22.4) | • 0.029 | • 14 (15.7) |
| • Mortality within 30 days of admissiona | • 0 | • 11 (19.0) | • 0.007 | • 11 (12.4) |
| All-cause mortality within 30 days of admission | 1 (1.6) | 20 (11.4) | 0.018 | 21 (8.8) |
| LRTI b(adults: 7 missing values) | 26 (40.6) | 85 (50.6) | 0.188 | 111 (47.8) |
| RSV-attributable pneumoniab | 12 (18.8) | 62 (36.9) | 0.008 | 74 (31.9) |
| • RSV documented from BALb | 2 (16.7) | 23 (37.1) | 0.024 | 25 (33.8) |
| • RSV-bacterial co-infection documented from BAL | 0 | 7 (11.3) | 0.020 | 7 (9.5) |
aRefers to patients admitted to hospital for an acute-respiratory-tract infection (ARTI)-attributable hospital admission (i.e excluded patients admitted to hospital for other reasons). bRefers to all patients seen in an ambulatory setting or admitted to hospital for their RSV infection or for another reason. BAL: Bonchoalveolar lavage, SD: Standard deviation, LRTI: Lower respiratory tract infection (adults 7 missing values); d: days. RSV-attributable pneumonia (7 missing values)