Fig. 1.

a Karyogram of DGAP294’s derivative chromosomes. Chromosomes 1, 4, 10, and 14 are depicted in blue, yellow, green, and red, respectively, with their corresponding G-bands (obtained from http://grch37.ensembl.org/Homo_sapiens/Location/Genome). BCA breakpoints are indicated with dashed black lines and bold numbers within solid squares (breakpoint numbers correspond to those shown in b). b DGAP294 BCA breakpoints' genomic coordinates and disrupted genes locations are reported in human genome version GRCh37/hg19