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. 2018 Mar 6;17:70. doi: 10.1186/s12943-018-0818-9

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — miR-190 is down-regulated and negatively correlated with SMAD2 expression in breast cancer tissues. a The miR-190 expression in TCGA breast invasive carcinoma and normal tissues. b The miR-190 expression in primary breast cancer tissues and paired normal breast tissues. c and d Kaplan-Meier analysis of the DFS (c) and OS (d) in patients with different miR-190 expression levels, as determined by RT-qPCR. e Kaplan-Meier analysis of the DFS in patients with different miR-190 expression levels, as determined using TCGA database. f The relationship between miR-190 and SMAD mRNA expression, as determined by RT-qPCR. g A model for the role of miR-190 in breast cancer metastasis. ***P < 0.001