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. 2018 Mar 1;9:361. doi: 10.3389/fmicb.2018.00361

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Copyright © 2018 Botas, Pérez-Redondo, Rodríguez-García, Álvarez-Álvarez, Yagüe, Manteca and Liras.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Expression profile of different genes in S. coelicolor M145 and S. coelicolor ΔargR. (A) Arginine biosynthesis genes. Profiles of argB, argC, argD, argJ, and argR are shown. Mg values for argR probe in mutant strain correspond to a nonexistent argR gene, and, thus serve to assess Mg values reflecting lack of expression. (B) Pyrimidine biosynthesis genes. Only pyrAa, pyrA, pyrB, and SCO1485 are shown as a model. (C) Profile of glnII amtB, glnK, and glnD as model of nitrogen metabolism genes. (D) Expression profile of nar3 genes. S. coelicolor M145 genes (black lines) and S. coelicolor ΔargR genes (gray lines).