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Histological observation of new bone formation around the implant on days 14 (A, B) and 21 (C, D) following discontinuation of simvastatin. New bone formation in the experimental group (A, C) was clearly lower than that in the control group (B, D). Toluidine blue staining; new bone is visualized in dark red; scale bar = 1 mm. Bone‐to‐implant contact was also measured (E) and was found to be lower in the experimental group at day 14.
