Table 3.

Sample size estimation for a future study that examines salivary intercellular ATP and plaque total ATP assessment

	AUC saliva i‐ATP	AUC plaque t‐ATP	Type I error	Type II error	Expected ratio of samples (pos/neg)	Number of negative samples required	Number of positive sample required	Total number of samples required
MS	0.823	0.774	0.05	0.2	2	394	788	1,182

Note. This estimation is based on comparing the area under an ROC curve (AUC) with a null hypothesis (0.5) value. The sample size takes into account the required significance level, power (0.80) of the test, and the AUC found in this study. ATP = adenosine triphosphate; ROC = receiver operating characteristic.