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. Author manuscript; available in PMC: 2018 Mar 6.
Published in final edited form as: Adv Exp Med Biol. 2017;1043:199–213. doi: 10.1007/978-3-319-70178-3_10

Fig. 1.

Fig. 1

Sex-dependent VMH functions are mediated by ERα-expressing VMHvl neurons. Within the hypothalamus, the VMH (red-shaded region) controls multiple aspects of metabolism and behavior. Whereas leptin receptor (LEPR) and insulin receptor (IR) expression overlap with SF-1 and regulate metabolism in both males and females, sex-dependent functions of the VMH are mediated by ERα-expressing VMH neurons (Nissl-stained image adapted from the Allen Brain Atlas)