Table 3. Univariate and multivariate analyses for analysis for overall survival and progression-free survival in patients with a high RDW ≥ 15.5% at diagnosis.

Variable	Overall survival			Progression free survival
	Univariate analyses p-value	HR (95% CI)	Multivariate analyses p-value	Univariate analyses p-value	HR (95% CI)	Multivariate analyses p-value
Sex, male	0.098			0.106
Age > 60 years	0.818			0.737
ECOG PS > 2	1.000			1.000
ISS stage	0.034	0.208 (0.049–0.886)	0.034	0.005	0.111 (0.024-0.520)	0.005
DS stage	0.401			0.857
Hemoglobin < 100 g/L	0.313			0.829
Creatinine > 176.8 μmol/L	0.655			0.821
Calcium > 2.75 mmol/L	0.999			0.358
Albumin < 35 g/L	0.282			0.254
β2-microglobulin > 5.5 mg/L	0.012	22.364 (1.689–296.189)	0.018	0.370
BM plasma cell ≥ 30%	0.329			1.000
osteolytic bone lesions ≥ 3	0.500			0.950
SCT	0.145			0.107
RDW ≥ 15.5% after treatment	0.012	5.263 (1.055–7.462)	0.044	0.037	3.891 (1.083-13.889)	0.034
RDW maintain at high level after treatment	0.034	1.308 (0.162–10.526)	0.800	0.397