Table 2. Multivariate analysis for PFS and OS in systemic T-cell NHL patients.
Factors | Multivariate for PFS | Multivariate for OS | ||||||
---|---|---|---|---|---|---|---|---|
HR (95% Cl) | P value | HR (95% Cl) | P value | HR (95% Cl) | P value | HR (95% Cl) | P value | |
Proportion of involved areas (%) | ||||||||
0-50 | 1.00 | 1.00 | ||||||
51-100 | 0.53 (0.27–1.03) | 0.0627 | 0.55 (0.27–1.12) | 0.1011 | ||||
Pattern of expression | ||||||||
Negative or Stromal only | 1.00 | 1.00 | ||||||
Vascular plus Stromal | 0.52 (0.25–1.08) | 0.0785 | 0.41 (0.19–0.88) | 0.0228 | ||||
Age | ||||||||
≤ 60 | 1.00 | 1.00 | 1.00 | 1.00 | ||||
> 60 | 1.56 (0.70–3.51) | 0.2800 | 1.31 (0.58–2.94) | 0.5158 | 1.92 (0.83–4.42) | 0.1256 | 1.59 (0.71–3.54) | 0.2591 |
Gender | ||||||||
Female | 1.00 | 1.00 | 1.00 | 1.00 | ||||
Male | 1.17 (0.59–2.31) | 0.6506 | 1.33 (0.66–2.66) | 0.4218 | 1.54 (0.75–3.14) | 0.2366 | 1.81 (0.87–3.80) | 0.1144 |
IPI | ||||||||
Low | 1.00 | 1.00 | 1.00 | 1.00 | ||||
Interm-Low | 1.71 (0.61–4.81) | 0.3121 | 1.88 (0.68–5.22) | 0.226 | 1.96 (0.66–5.79) | 0.2239 | 2.23 (0.77–6.47) | 0.1387 |
Interm-High | 1.81 (0.67–4.92) | 0.2446 | 2.39 (0.91–6.29) | 0.0774 | 1.82 (0.61–5.42) | 0.2855 | 2.36 (0.83–6.75) | 0.1089 |
High | 4.10 (1.57–10.68) | 0.0039 | 5.99 (2.12–16.92) | 0.0007 | 5.10 (1.92–13.54) | 0.0011 | 8.41 (2.93–24.14) | <.0001 |
Legend: NHL: non-Hodgkin lymphoma; PFS: progression free survival; OS: overall survival.