Table 1. List of candidate prognostic biomarkers for pancreatic cancer.
| Entry | Gene | DDA | PRM | Description | |||||
|---|---|---|---|---|---|---|---|---|---|
| LS Freq. | SS Freq. | P value | SS/LS Fold change | Pep. no. | P value | SS/LS Fold change | |||
| P14780 | MMP9 | 10 | 9 | 0.026 | 3.62 | 2 | 0.045 | 4.44 | Matrix metalloproteinase-9 |
| O95833 | CLIC3 | 1 | 6 | 0.039 | 3.25 | 2 | 0.010 | 3.42 | Chloride intracellular channel protein 3 |
| P22894 | MMP8 | 1 | 6 | 0.029 | 4.28 | 1 | 0.046 | 3.06 | Neutrophil collagenase |
| P24158 | PRTN3 | 7 | 9 | 0.022 | 3.85 | 2 | 0.031 | 2.98 | Myeloblastin |
| O15460-2 | P4HA2 | 6 | 9 | 0.025 | 2.88 | 2 | 0.029 | 2.66 | Isoform IIa of Prolyl 4-hydroxylase subunit alpha-2 |
| P07996 | THBS1 | 10 | 9 | 0.015 | 2.46 | 2 | 0.028 | 2.01 | Thrombospondin-1 |
| P02751 | FN1 | 10 | 9 | 0.029 | 2.07 | 2 | 0.034 | 1.92 | Fibronectin |
| A8K7I4 | CLCA1 | 5 | 0 | 0.015 | 0.08 | 1 | 0.029 | 0.05 | Calcium-activated chloride channel regulator 1 |
| P09327 | VIL1 | 10 | 5 | 0.004 | 0.11 | 2 | 0.008 | 0.12 | Villin-1 |
| O00748 | CES2 | 5 | 0 | 0.008 | 0.15 | 2 | 0.029 | 0.16 | Cocaine esterase |
| O75208 | COQ9 | 8 | 2 | 0.004 | 0.27 | 2 | 0.004 | 0.19 | Ubiquinone biosynthesis protein COQ9, mitochondrial |
| Q5R3I4 | TTC38 | 10 | 5 | 0.017 | 0.21 | 1 | 0.035 | 0.20 | Tetratricopeptide repeat protein 38 |
| P56470 | LGALS4 | 10 | 8 | 0.003 | 0.19 | 2 | 0.005 | 0.23 | Galectin-4 |
| P10645 | CHGA | 7 | 2 | 0.038 | 0.23 | 2 | 0.025 | 0.27 | Chromogranin-A |
| Q9BW30 | TPPP3 | 9 | 1 | 0.001 | 0.10 | 1 | 0.000 | 0.28 | Tubulin polymerization-promoting protein family member 3 |
| Q9H0R4 | HDHD2 | 10 | 5 | 0.005 | 0.22 | 2 | 0.026 | 0.30 | Isoform 2 of Haloacid dehalogenase-like hydrolase domain-containing protein 2 |
| Q6UXN9 | WDR82 | 7 | 2 | 0.039 | 0.22 | 1 | 0.023 | 0.31 | WD repeat-containing protein 82 |
| P16422 | EPCAM | 8 | 2 | 0.012 | 0.20 | 1 | 0.021 | 0.33 | Epithelial cell adhesion molecule |
| Q96LJ7 | DHRS1 | 7 | 1 | 0.007 | 0.24 | 1 | 0.017 | 0.37 | Dehydrogenase/reductase SDR family member 1 |
| P45954 | ACADSB | 9 | 3 | 0.017 | 0.15 | 2 | 0.026 | 0.38 | Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial |
| Q96IU4 | ABHD14B | 10 | 9 | 0.007 | 0.31 | 2 | 0.013 | 0.46 | Alpha/beta hydrolase domain-containing protein 14B |
| Q6UXI9-6 | NPNT | 10 | 3 | 0.008 | 0.25 | 1 | 0.016 | 0.46 | Isoform 6 of Nephronectin |
| P08294 | SOD3 | 10 | 9 | 0.015 | 0.48 | 2 | 0.003 | 0.47 | Extracellular superoxide dismutase [Cu-Zn] |
| Q8N335 | GPD1L | 9 | 4 | 0.030 | 0.16 | 2 | 0.010 | 0.47 | Glycerol-3-phosphate dehydrogenase 1-like protein |
| Q7Z7H5 | TMED4 | 10 | 4 | 0.002 | 0.13 | 2 | 0.040 | 0.48 | Transmembrane emp24 domain-containing protein 4 |
Abbreviations: DDA:data-dependent acquisition; PRM:parallel reaction monitoring; LS: long survival; SS: short survival; Pep. No: number of peptides for proteins in the PRM panel. Freq.: number (frequency) of cases in which the protein was detected.