Figure 4. Significantly enriched GSEA signatures common and sustained at the 4- and 24- hour treatment time points.

GSEA for the Hallmark gene sets for transcriptional changes in NGP cells when treated with 3 µM HCI-2509 showed significant positive and negative enrichment for four gene sets that were common between the 4 and 24 hour time points. (A) GSEA plots at the 4 hour treatment time point. (B) GSEA plots at the 24 hour treatment time point.