Table 2.

KEGG modules whose relative abundance differed by tumor grade

KEGG modules	Grade 2 (moderately differentiated)	Grade 3 (poorly differentiated)	P (Bonferroni-adjusted)
P<0.05
Carbohydrate Metabolism	0.158(0.142–0.166)	0.142(0.137–0.153)	0.02
Metabolism	0.042(0.033–0.048)	0.034(0.032–0.039)	0.04
Transcription	0.037(0.025–0.041)	0.025(0.022–0.034)	0.04
Environmental Adaptation	0.003(0.002–0.004)	0.004(0.003–0.004)	0.04
Circulatory System	0.001(0.000–0.003)	0.002(0.001–0.003)	0.05
0.05<P<0.1
Enzyme Families	0.032(0.029–0.033)	0.029(0.028–0.031)	0.08
Digestive System	0.001(0.000–0.001)	0.000(0.000–0.001)	0.06
Folding Sorting and Degradation	0.045(0.042–0.056)	0.055(0.048–0.058)	0.07
Energy Metabolism	0.098(0.089–0.116)	0.116(0.101–0.121)	0.08
Cell Motility	0.056(0.043–0.084)	0.087(0.065–0.097)	0.08
Genetic Information Processing	0.051(0.047–0.067)	0.066(0.055–0.071)	0.06

P-values were based on Wilcoxon rank-sum test with Bonferroni adjustment