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. 2017 Jun 14;26(2):167–174. doi: 10.4062/biomolther.2017.054

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Copyright © 2018 The Korean Society of Applied Pharmacology

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 4. — Differences in hepatic sulfur amino acid metabolism between 2- and 30-month-old mice. MAT, methionine adenosyltransferase; SAHH, S-adenosylhomocysteine hydrolase; BHMT, betaine homocysteine methyltransferase; MS, methionine synthase; MTHFR, methylenetetrahydrofolate reductase; CβS, cystathionine β-synthase; CγL, cystathionine γ-lyase; CDO, cysteine dioxygenase; CDC, cysteine sulfinic acid decarboxylase; GCL, γ-glutamylcysteine ligase; THF, tetrahydrofolate; ND, not determined. Arrows represent situation in 30-month-old mice relative to 2-month-old mice.