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. 2018 Mar 6;13(3):e0193768. doi: 10.1371/journal.pone.0193768

Table 2. Correlation coefficient matrix of immunoglobulins to flagellin and lipolysaccharide with measures of systemic inflammation and enteric inflammation & regeneration.

At 6 months At 9 months
Systemic inflammation Enteric inflammation & regeneration Systemic inflammation Enteric inflammation & regeneration
CRP
mg/L
n = 320
AGP
mg/dL
n = 307
Ferritin
ng/mL
n = 320
MPO
ng/mL
n = 322
NEO
nmol/L
n = 322
Reg1b stool
μg/g
n = 319
Reg1b serum
pg/mL
n = 315
CRP
mg/L
n = 369
AGP
mg/dL
n = 308
Ferritin
ng/mL
n = 369
MPO
ng/mL
n = 377
NEO
nmol/L
n = 373
Reg1 stool
μg/g
n = 316
Reg1 serum
pg/mL
n = 316
At 6 months At 9 months
Anti-Flic IgA, OD 0.02 0.11 0.02 -0.03 0.06 0.002 0.21** 0.01 0.15* 0.04 0.07 -0.10 0.04 0.04
Anti-Flic IgG, OD 0.04 0.06 0.02 0.01 0.02 0.02 0.10 0.01 0.07 0.16* 0.07 -0.18** 0.11 0.05
Anti-LPS IgA, OD 0.12* 0.18* 0.06 -0.04 -0.03 0.04 0.20** 0.05 0.11 0.03 0.11* -0.10 0.07 0.02
Anti-LPS IgG, OD 0.10 0.12* 0.03 -0.02 -0.03 -0.03 0.08 0.02 -0.005 0.10 0.03 -0.17* 0.10 -0.04

Note: Values are Spearman’s rank-order correlation coefficient.

***P<0.0001

**P<0.001

*P-value<0.05.

Abbreviations: Flagellin = Flic; Immunoglobulin = Ig; Lipopolysacccharide = LPS; alpha glycoprotein = AGP; C-reactive protein = CRP; Myeloperoxidase = MPO; Neopterin = NEO; regenerating gene 1β = REG1b