Table I.
Association between SNP and ferritin levels.
| Gene | SNP name | Overall p-value* | |||
|---|---|---|---|---|---|
|
| |||||
| Male | Female | ||||
|
| |||||
| Before† | After‡ | Before† | After‡ | ||
|
| |||||
| BTBD9 | rs9296249 | 0.641 | 0.996 | ||
| rs3923809 | 0.027 | 0.073 | 0.748 | ||
|
| |||||
| TMPRSS6 | rs855791 | 0.874 | 0.869 | ||
| rs4820268 | 0.980 | 0.043 | 0.025 | ||
|
| |||||
| TFR2 | rs7385804 | 0.512 | 0.480 | ||
|
| |||||
| TF | rs3811647 | 0.824 | 0.686 | ||
| rs1799852 | 0.260 | 0.736 | |||
| rs2280673 | 0.473 | 0.377 | |||
|
| |||||
| BMP2 | rs235756 | 0.029 | 0.038 | 0.711 | |
|
| |||||
| SMIM1 | rs1175550 | 0.961 | 0.425 | ||
*
Overall p-value <0.05 indicates this particular SNP has a statistically significant impact on ferritin levels;
†
before adjusting for donor parameters;
‡
after adjusting for significant donor parameters (donation-induced iron loss and time since previous donation for male donors; age, donation-induced iron loss and time since previous donation for female donors); Shaded cells show SNP significantly (p<0.05) associated with ferritin levels.
SNP: single nucleotide polymorphism.