Table II.

Association between ferritin levels and BTBD9 rs3923809 or BMP2 rs235756 in male donors.

SNP	Before adjusting for donor parameters Ferritin ≤15 ng/mL
	GG vs AA		AG vs AA
	OR (95% CI)	p-value	OR (95% CI)	p-value
rs3923809	1.491(0.395–5.632)	0.556	1.438 (0.651–3.174)	0.369
rs235756	0.297 (0.037–2.406)	0.255	1.967 (0.865–4.471)	0.106
		Ferritin >100 ng/mL
rs3923809	3.253 (1.443–7.333)	0.004	2.091 (1.186–3.688)	0.011
rs235756	0.434 (0.172–1.091)	0.076	0.742 (0.436–1.262)	0.271
		After adjusting for significant donor factors§ Ferritin ≤15 ng/mL
rs3923809	1.949 (0.493–7.709)	0.342	1.565 (0.682–3.592)	0.291
rs235756	0.327 (0.039–2.768)	0.305	2.077 (0.868–4.973)	0.101
		Ferritin >100 ng/mL
rs3923809	2.715 (1.164–6.330)	0.021	1.967 (1.097–3.525)	0.023
rs235756	0.448 (0.176–1.141)	0.092	0.724 (0.417–1.254)	0.249

Shaded cells indicate the genotype was significantly (p<0.05) associated with this particular ferritin group compared to the wild-type (AA) genotype;

^§Significant donor factors include time since previous donation and donation-induced iron loss in the previous 12 months.

SNP: single nucleotide polymorphism; OR: odds ratio; CI: confidence interval.