Table III.

Association between ferritin levels and TMPRSS6 rs4820268 in female donors.

Before adjusting for donor parameters Ferritin ≤8 ng/mL
GG vs AA		AG vs AA
OR (95% CI)	p-value	OR (95% CI)	p-value
1.808 (0.580–5.641)	0.307	3.348 (1.328–8.438)	0.010
Ferritin >60 ng/mL
0.775 (0.339–1.769)	0.545	0.890 (0.379–1.462)	0.391
After adjusting for significant donor factors* Ferritin ≤8 ng/mL
2.073 (0.646–6.647)	0.220	3.443 (1.314–9.021)	0.012
Ferritin >60 ng/mL
0.573 (0.238–1.378)	0.214	0.548 (0.265–1.133)	0.104

Shaded cells indicate the genotype was significantly (p<0.05) associated with this particular ferritin group compared to the wild-type (AA) genotype;

^*Significant donor factors include age, time since previous donation and donation-induced iron loss in the previous 12 months.

SNP: single nucleotide polymorphism; OR: odds ratio; CI: confidence interval.