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. 2018 Feb 2;7:e33432. doi: 10.7554/eLife.33432

Figure 13. Effects of conditional expression of ADGRG2 wild-type or its selective G-subtype signaling mutants in Adgrg2-/Y mice on the fluid reabsorption of efferent ductules.

Figure 13.

(A) Effects of the expression of the ADGRG2-WT adenovirus on the diameter of the ligated efferent ductules derived from the WT or Adgrg2-/Y mice. (B–F) Effects of the expression of adenovirus encoding different ADGRG2 mutants on the diameter of the ligated efferent ductules derived from the WT (n = 12) or Adgrg2-/Y (n = 12) mice. (A–F) *p<0.05, **p<0.01, ***p<0.001; Adgrg2-/Y mice infected with the empty adenovirus compared with WT mice infected with the empty adenovirus. #p<0.05, ##p<0.01, ###p<0.001; Adgrg2-/Y mice infected with the adenovirus encoding different ADGRG2 constructs compared with Adgrg2-/Y mice infected with the control adenovirus. n.s., no significant difference.