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. 2018 Jan 30;159(3):1537–1546. doi: 10.1210/en.2017-03176

Figure 6.

Figure 6.

An NMDAR antagonist normalizes the CUMS-induced elevation of circulating CORT levels. (A) Summary data show plasma CORT levels during the basal condition and before and after bilateral microinjection of the NMDAR antagonist memantine into the PVN in unstressed rats (n = 6) and CUMS rats (n = 6). (B) Images of coronal brain slice showing the microinfusion sites marked by fluorescent microspheres (0.04 μm, wavelength 580 nm, red) in the PVN in (a) light optics and (b) fluorescent illumination. *P < 0.05 compared with the basal value within the same group; #P < 0.05 compared with the respective values at the same time in unstressed rats. 3V, third ventricle.