Small RNA-seq statistics. (A) Distribution of small RNA-seq reads among different RNA classes. The two largest sources of small RNA reads are annotated miRNAs (33%) and unannotated reads from Ref-Seq loci (34%). (B) Read-length distribution of small-RNA sequencing peaked at 23 nt, which corresponds to the length of mature miRNAs. piRNA, PIWI-interacting RNA; rRNA, ribosomal RNA; scaRNA, small Cajal body-specific RNA; snoRNA, small nucleolar RNA; tRNA, transfer RNA.