Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Mar 6;7:e31715. doi: 10.7554/eLife.31715

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018, Matsunaga et al

This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.

PMC Copyright notice

Figure 1. — (A) Simulation box and a side view of AcrB embedded in a palmitoyloleoyl phosphatidylethanolamine (POPE) lipid bilayer. A drug (minocycline) is represented by spheres. (B) Porter domains of the crystal structure viewed from the cell exterior. The protomers in cyan, magenta and lime represent the Binding, Extrusion, and Access states, respectively. (C) The transmembrane domain viewed from the cell exterior. Key residues that are related to proton translocation are represented by sticks. (D) Close-up view of the key residues. (E) Schematics of the simulation systems. The protonated D408 is denoted by D408p. System 1 has D408p in the Protomer II. System 2 has D408p in the Protomer I.