Table 6. Univariate and multivariate analysis results of blood urea nitrogen/creatinine levels by group.
| Variable | Normal group (n=125) | Abnormal group (n=3) | Univariate | Multivariate | ||
|---|---|---|---|---|---|---|
| HR (95% CI) | p-value | HR (95% CI) | p-value | |||
| Age (yr) | 40.90±14.17 | 73.00±4.36 | 1.174 (1.068~1.370) | 0.007* | 1.209 (1.065~1.562) | 0.032* |
| Sex | ||||||
| Male | 69 (55.2) | 2 (66.7) | 0.593 (0.028~6.190) | 0.670 | ||
| Female | 56 (44.8) | 1 (33.3) | ||||
| BMI (kg/m2)† | 24.21±4.03 | 26.13±1.57 | 1.127 (0.791~1.584) | 0.481 | ||
| Duration of disease (mo) | 93.21±104.33 | 188.00±90.07 | 1.006 (0.997~1.015) | 0.156 | ||
| PASI score‡ | ||||||
| ≤10 | 42 (38.5) | 1 (33.3) | 1.067 (0.976~1.147) | 0.099 | ||
| >10 | 67 (61.5) | 2 (66.7) | ||||
| Total medication period (d) | 343.63±339.73 | 233.67±319.93 | 0.998 (0.989~1.002) | 0.557 | ||
| Cumulative dose (g) | 45.80±42.99 | 45.22±65.37 | 1 (1~1) | 0.875 | ||
| Underlying diseases | ||||||
| Diabetes§ | 8 (6.4) | 0 (0.0) | 0.487 (0.047~65.460) | 0.680 | ||
| Hypertension§ | 14 (11.2) | 0 (0.0) | 0.817 (0.079~109.818) | 0.908 | ||
| Dyslipidemia§ | 9 (7.2) | 0 (0.0) | 0.582 (0.056~78.299) | 0.757 | ||
| Chronic hepatitis B infection§ | 3 (2.4) | 0 (0.0) | 0.184 (0.018~24.718) | 0.332 | ||
| Kidney disease | 0 (0.0) | 1 (33.3) | 0.008 (0~0.205) | 0.001* | 0.029 (0.001~0.807) | 0.022* |
| Others∥ | 8 (6.4) | 1 (33.3) | 0.655 (0.030~6.841) | 0.114 | ||
Values are presented as mean±standard deviation or number (%). BMI: body mass index, PASI: psoriasis area and severity index, HR: hazard ratio, CI: confidence interval. *p<0.05. †Including only patients for whom BMI (total=57, normal=55, abnormal=2) was available. ‡Including only patients for whom PASI score (total=112, normal=109, abnormal=3) was available. §Firth's correction was applied. ∥Angina, aortic dissection, autism, brain hemorrhage, stroke, thyroid disease.