Table 3. Histopathologic findings of 20 patients with folliculotropic mycosis fungoides.
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | Patient no. (n=20) | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Folliculotropism | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | 20 (100) |
| Epidermotropism | + | + | + | − | + | + | + | + | + | − | + | + | + | + | + | − | + | + | + | + | 17 (85.0) |
| Follicular mucinosis | + | − | − | + | − | − | − | − | + | − | − | − | − | − | + | − | + | − | + | + | 7 (35.0) |
| Syringotropism | − | − | − | − | + | − | − | − | − | − | − | − | − | − | − | − | − | − | − | − | 1 (5.0) |
| Perifollicular cell infiltrate | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | 20 (100) |
| Follicle destruction | + | − | − | − | + | − | − | − | − | + | + | − | − | + | + | − | − | + | − | − | 7 (35.0) |
| Cystic dilatation | + | + | − | − | − | − | − | − | − | − | + | − | − | − | + | + | + | − | − | − | 6 (30.0) |
| Foreign body granuloma | + | − | − | − | − | − | − | − | − | + | − | − | − | − | − | − | − | − | − | − | 2 (10.0) |
| Large cell transformation | − | − | − | − | − | − | − | + | + | − | − | − | + | − | − | + | − | − | − | − | 4 (20.0) |
| Tissue eosinophilia | +(E) | − | − | − | +(M) | − | − | +(E) | − | +(E) | − | − | − | +(E) | +(E) | +(E) | +(F) | − | +(E) | − | 9 (45.0) |
| Eosinophil infiltrate | |||||||||||||||||||||
| Eosinophilic folliculitis | + | − | − | − | + | − | − | + | − | + | − | − | − | + | − | + | − | − | + | − | 7 (35.0) |
| Epidermis | + | − | − | − | − | − | − | − | − | − | − | − | − | + | + | + | − | − | − | − | 4 (20.0) |
| Dermis | + | − | − | − | + | − | − | + | − | + | − | − | − | + | + | + | + | − | + | − | 9 (45.0) |
| Plasma cell infiltrate | + | + | − | + | + | − | + | + | − | + | + | − | + | − | − | + | − | + | − | − | 11 (55.0) |
| Involvement of subcutaneous fat | − | − | − | − | + | − | − | − | − | + | − | − | − | − | − | + | − | − | − | − | 3 (15.0) |
| Pautrier's microabscess | + | − | − | − | − | − | − | + | + | + | − | − | + | + | − | − | − | − | − | + | 7 (35.0) |
| Lymphocytes aligned along basal cells | + | + | + | − | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | 19 (95.0) |
| Intraepidermal lymphocytes larger than lymphocytes in dermis | + | − | + | − | − | − | − | − | − | − | − | − | + | − | − | − | − | − | − | − | 3 (15.0) |
| “Haloed” lymphocyte | + | + | + | − | + | + | + | + | + | − | + | + | + | + | + | + | + | + | + | + | 18 (90.0) |
| Atypical cells with hyperchromatic nuclei | + | + | + | + | + | + | + | + | + | + | − | + | + | + | + | + | + | + | + | + | 19 (95.0) |
| Coarse collagen bundles in papillary dermis | + | + | + | − | − | + | + | + | + | + | + | + | + | + | + | − | + | + | + | + | 17 (85.0) |
Values are presented as number (%). F (few): <5 eosinophils per histologic section of a standard 4 mm punch biopsy, M (moderate): 5~20 eosinophils per histologic section of a standard 4 mm punch biopsy, E (extensive): >20 eosinophils per histologic section of a standard 4 mm punch biopsy.