Table 1. Characteristics of the Study Groups.
Spinal Cord Injury | Able-Bodied | ||||
---|---|---|---|---|---|
Eugonadal | Hypogonadal | Eugonadal | Hypogonadal | p value | |
|
|||||
n | 16 | 14 | 11 | 27 | - |
Age (years) | 33 ± 7 | 41 ± 10 | 36 ± 7 | 36 ± 9 | 0.06 |
Height (m) | 1.79 ± 0.08 | 1.78 ± 0.07 | 1.82 ± 0.10 | 1.76 ± 0.08 | NS |
Weight (kg) | 88.1 ± 20.1 | 81.7 ± 15.2 | 87.6 ± 11.3 | 83.6 ± 14.0 | NS |
BMI (kg/m2) | 27.3 ± 4.5 | 25.4 ± 4.0 | 26.4 ± 3.3 | 26.8 ± 3.8 | NS |
DOI (years) | 11 ± 7 | 12 ± 10 | - | - | NS |
Paraplegia/Tetraplegia (n) | 11/5 | 10/4 | - | - | NS |
Total Testosterone (nmol/l) | 17.4 ± 4.4 | 7.4 ± 3.8 *,† | 16.7 ± 4.3‡ | 7.7 ± 2.3¶ | <0.0001 |
Luteinizing Hormone (mIU/ml) | |||||
GnRH 10 μg | 1.4 ± 1.0 | 2.0 ± 1.6 | 2.5 ± 1.6 | 2.5 ± 2.7 | NS |
GnRH 50 μg | 1.6 ± 1.4 | 2.1 ± 2.5 | 3.3 ± 2.6 | 2.5 ± 5.4 | NS |
GnRH 100 μg | 3.3 ± 3.0 | 2.0 ± 2.1 | 2.8 ± 1.9 | 5.2 ± 8.9 | NS |
Follicle Stimulating Hormone (mIU/ml) | |||||
GnRH 10 μg | 1.4 ± 1.1 | 2.0 ± 2.2 | 2.9 ± 2.7 | 3.6 ± 3.3 | NS |
GnRH 50 μg | 1.6 ± 1.6 | 1.7 ± 2.2 | 3.2 ± 3.9 | 3.2 ± 3.6 | NS |
GnRH 100 μg | 2.7 ± 2.6 | 1.8 ± 1.8$ | 2.3 ± 2.8 | 5.0 ± 3.7 # | <0.01 |
Data are presented as group mean ± SD. Abbreviations: BMI=body mass index; DOI= duration of injury; GnRH= gonadotropin releasing hormone; NS= not significant; kg= kilograms; nmol/l= nanomoles per liter; mIU/ml= milli-international units per milliliter; μg= micrograms.
p<0.0001: SCI-Eugonadal vs. SCI-Hypogonadal;
p<0.0001: AB-Eugonadal vs. SCI-Hypogonadal;
p<0.0001: AB-Eugonadal vs. SCI-Hypogonadal;
p<0.0001: AB-Eugonadal vs AB-Hypogonadal;
p<0.01: SCI-Hypogonadal vs. AB-Hypogonadal;
p<0.05: SCI-Hypogonadal vs. SCI-Eugonadal.