Table 3.

Diagnostic performance of hyperspectral reflectance imaging, autofluorescence imaging, 2-NBDG fluorescence imaging and proflavine fluorescence imaging for the distinction of non-neoplastic and neoplastic tissue of ex vivo tongue and the diagnostic performance of hyperspectral reflectance imaging and autofluorescence imaging of in vivo tongue

	Imaging Method	AUC	Accuracy	Sensitivity	Specificity
In Vivo	HSI	0.84±0.05	78%±5%	78%±5%	78%±5%
	Autofluorescence	0.84±0.06	78%±5%	78%±4%	77%±9%
	Autofluorescence(R/G)	0.43±0.10	48%±6%	48%±6%	47%±12%
Ex Vivo	2-NBDG	0.91±0.04	84%±3%	85%±3%	84%±6%
	Proflavine	0.89±0.03	82%±3%	83%±3%	81%±5%
	HSI	0.86±0.06	79%±6%	79%±7%	79%±5%
	Autofluorescence	0.87±0.03	80%±4%	80%±6%	81%±3%
	Autofluorescence(R/G)	0.49±0.19	50%±14%	50%±17%	54%±12%
	2-NBDG (Mean)	0.75±0.23	70%±17%	70%±18%	71%±19%
	Proflavine (Std)	0.49±0.15	54%±9%	56%±12%	49%±20%