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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: J Orthop Res. 2017 Dec 5;36(2):808–815. doi: 10.1002/jor.23772

Figure 4.

Figure 4

Substrate type and cellular contractility influence YAP nuclear localization in MSCs. (A) YAP staining (red), F-actin staining (green), and nuclear staining (blue), scale bar = 20 μm. (B) Quantification of nuclear localization at different passages and with inhibition of contractility (n = ~20, *: p<0.05 vs. TCP using two-way ANOVA across groups and passage number only with Fisher’s LSD, +: p<0.05 vs. P0 TCP from one-way ANOVA across only TCP groups, Fisher’s LSD, Y27: Y27632, Rho kinase inhibitor, mean ± S.E.M.).