Table 2.

Regression results examining association between DII and memory function (N=1,723), NHANES, 2011–2014.

	Unadjusted		Adjusted
CERAD Word Learning	b	95% CI	b	95% CI
Trial 1
DII Q2 vs. Q1	−.03	−.34, .27	−.03	−.30, .24
DII Q3 vs. Q1	.09	−.26, .44	.01	−.26, .29
DII Q4 vs. Q1	−.16	−.50, .18	−.11	−.44, .21
Trial 2
DII Q2 vs. Q1	−.10	−.42, .20	−.09	−.37, .17
DII Q3 vs. Q1	−.08	−.42, .25	−.16	−.43, .10
DII Q4 vs. Q1	−.34	−.67, −.01	−.30	−.66, .05
Trial 3
DII Q2 vs. Q1	.16	−.20, 54	.18	−.18, .55
DII Q3 vs. Q1	.01	−.31, .34	−.04	−.32, .23
DII Q4 vs. Q1	.03	−.36, .42	.07	−.32, .46
Sum of Trials 1–3
DII Q2 vs. Q1	.01	−.88, .92	.05	−.76, .88
DII Q3 vs. Q1	.02	−.87, .92	−.19	−.87, .48
DII Q4 vs. Q1	−.47	−1.40, .46	−.34	−1.28, .59
Delay Trial
DII Q2 vs. Q1	−.17	−.65, .29	−.18	−.59, .22
DII Q3 vs. Q1	−.02	−.43, .39	−.16	−.53, .20
DII Q4 vs. Q1	−.39	−.76, −.03	−.39	−.79, .00
Animal Fluency
DII Q2 vs. Q1	−.23	−1.36, .90	−.33	−1.21, .54
DII Q3 vs. Q1	−.66	−1.68, .35	−1.00	−1.89, −.12
DII Q4 vs. Q1	−1.22	−2.34, −.10	−1.18	−2.17, −.20
DSST
DII Q2 vs. Q1	−.80	−3.88, 2.27	−.66	−3.15, 1.82
DII Q3 vs. Q1	−1.16	−4.73, 2.40	−1.84	−4.68, .99
DII Q4 vs. Q1	−3.93	−6.86, −1.01	−2.80	−5.58, −.02

DSST, Digit Symbol Substitution Test

Q, Quartile

Bold text indicates statistical significance (P<0.05)

In the adjusted model, covariates included age (yrs; continuous), sex (male/female), race-ethnicity (Mexican American, other Hispanic, non-Hispanic white, non-Hispanic black, and other), measured body mass index (kg/m²; continuous), self-reported smoking status (never, former, current), self-reported average hours of sleep each night (hrs/night; continuous), self-reported engagement in leisure-time moderate-to-vigorous physical activity (min/week) assessed from the Global Physical Activity Questionnaire, and PHQ-9 assessed depression symptomology (range = 0–27; continuous).