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Summary of rare variants harbored in exonic regions and upstream regions of sequenced genes involved in retinoid related metabolism and signaling
| Gene symbol | In exonic | In upstream | ||||||
|---|---|---|---|---|---|---|---|---|
| NTD | Control | P value | FDR correction Q value | NTD | Control | P value | FDR correction Q value | |
| CYP26A1 | 3 | 0 | 0.2878 | 0.8634 | 6 | 2 | 0.7170 | 1 |
| CYP26B1 | 12 | 1 | 0.0215 | 0.129 | 1 | 0 | 1 | 1 |
| CRABP1 | 1 | 0 | 1 | 1 | 4 | 0 | 0.3037 | 0.9111 |
| CRABP2 | 0 | 0 | 1 | 1 | 2 | 0 | 0.5249 | 1 |
| RARA | 0 | 0 | 1 | 1 | 2 | 1 | 1 | 1 |
| ALDH1A2 | 2 | 0 | 0.5249 | 1 | 6 | 0 | 0.0871 | 0.5226 |
FDR: False discovery rate
