Table 3. Malignant and Benign Thyroid Incidentalomas Characteristics at 18F-FDG PET/CT.
| Mean ± SD | Malignant Median | Range | Mean ± SD | Benign Median | Range | P* | AUC (95% CI) | |
|---|---|---|---|---|---|---|---|---|
| SUVmax | 11.3 ± 8.4 | 9.800 | 2.10, 47.00 | 4.8 ± 5.3 | 3.60 | 1.40, 26.90 | < 0.001 | 0.866 (0.783, 0.950) |
| MTV 2.5 (cm3) | 3.3 ± 5.2 | 1.370 | 0.10, 26.40 | 0.8 ± 0.9 | 0.50 | 0.04, 3.60 | < 0.001 | 0.764 (0.667, 0.861) |
| MTV 3.0 (cm3) | 3.0 ± 4.7 | 1.245 | 0.07, 22.80 | 0.6 ± 0.7 | 0.34 | 0.03, 2.70 | < 0.001 | 0.796 (0.707, 0.886) |
| MTV 3.5 (cm3) | 2.8 ± 4.2 | 1.215 | 0.05, 20.10 | 0.5 ± 0.6 | 0.22 | 0.01, 2.35 | < 0.001 | 0.819 (0.735, 0.903) |
| MTV 4.0 (cm3) | 2.7 ± 4.0 | 1.185 | 0.04, 19.20 | 0.3 ± 0.5 | 0.13 | 0.01, 2.31 | < 0.001 | 0.872 (0.802, 0.942) |
| TLG 2.5 | 37.2 ± 92.8 | 10.140 | 0.16, 644.00 | 3.5 ± 7.1 | 0.84 | 0.05, 37.75 | < 0.001 | 0.827 (0.743, 0.911) |
| TLG 3.0 | 34.2 ± 86.1 | 9.270 | 0.13, 607.60 | 2.8 ± 6.6 | 0.74 | 0.03, 37.28 | < 0.001 | 0.851 (0.772, 0.930) |
| TLG 3.5 | 31.7 ± 79.7 | 8.790 | 0.10, 562.80 | 2.5 ± 6.4 | 0.53 | 0.01, 36.66 | < 0.001 | 0.867 (0.791, 0.942) |
| TLG 4.0 | 30.0 ± 75.5 | 8.635 | 0.07, 537.60 | 1.9 ± 6.2 | 0.27 | 0.01, 36.03 | < 0.001 | 0.895 (0.826, 0.963) |
*Mann–Whitney U test. AUC = areas under the curve, CI = confidence interval, MTV = metabolic tumor volume, SUVmax = maximum standardized uptake value, TLG = total lesion glycolysis, 18F-FDG PET/CT = fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography