Table 4. Comparisons of Various Quantitative Parameters Assessed by 18F-FDG PET/CT Characteristics of Malignant Thyroid Incidentalomas (n = 63).
Age (Years) | Male/Female | Diameter (cm) | SUVmax | MTV 2.5 (cm3) | MTV 3.0 (cm3) | MTV 3.5 (cm3) | MTV 4.0 (cm3) | TLG 2.5 | TLG 3.0 | TLG 3.5 | TLG 4.0 | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Papillary adenocarcinoma (n = 38) | 12/26 | |||||||||||
Mean ± SD | 47.1 ± 14.4 | 1.8 ± 0.9 | 11.8 ± 8.4 | 3.5 ± 5.2 | 3.2 ± 4.8 | 3.0 ± 4.5 | 2.9 ± 4.3 | 45.3 ± 113.9 | 41.8 ± 106.4 | 39.0 ± 98.9 | 37.1 ± 93.9 | |
Median | 48 | 1.55 | 9.95 | 1.335 | 1.28 | 1.25 | 1.205 | 9.1 | 8.7 | 8.5 | 10.345 | |
Range | 20, 83 | 0.7, 4.2 | 2.1, 47 | 0.1, 23 | 0.08, 21.7 | 0.08, 20.1 | 0.07, 19.2 | 0.16, 644.0 | 0.13, 607.6 | 0.13, 562.8 | 0.11, 537.6 | |
Medullary carcinoma (n = 8) | 4/4 | |||||||||||
Mean ± SD | 55.1 ± 8.8 | 2.0 ± 0.9 | 13.4 ± 11.4 | 5.0 ± 8.7 | 4.4 ± 7.5 | 4.0 ± 6.5 | 3.6 ± 5.8 | 51.2 ± 80.5 | 45.8 ± 69.7 | 41.5 ± 60.8 | 38.5 ± 55.4 | |
Median | 55 | 1.7 | 10.25 | 2.04 | 1.94 | 1.89 | 1.855 | 19.3 | 18.1 | 17.0 | 15.53 | |
Range | 39, 66 | 1.2, 4.1 | 3.9, 40 | 0.48, 26.4 | 0.42, 22.8 | 0.38, 19.8 | 0.33, 17.9 | 1.34, 240.2 | 1.18, 207.5 | 1.06, 180.2 | 0.92, 162.8 | |
Thyroid follicular adenocarcinoma (n = 10) | 3/7 | |||||||||||
Mean ± SD | 51.2 ± 18.6 | 1.7 ± 0.7 | 7.9 ± 7.3 | 2.5 ± 2.7 | 2.3 ± 2.6 | 2.1 ± 2.5 | 2.0 ± 2.3 | 12.2 ± 12.6 | 11.3 ± 12.1 | 10.7 ± 11.9 | 10.0 ± 11.3 | |
Median | 47.5 | 1.5 | 5.5 | 1.345 | 1.215 | 1.08 | 1.025 | 9.7 | 8.5 | 7.6 | 6.895 | |
Range | 28, 87 | 0.7, 3 | 3.9, 28.2 | 0.1, 7.62 | 0.07, 7.14 | 0.05, 6.6 | 0.04, 6.1 | 0.19, 36.2 | 0.13, 35.1 | 0.1, 34.6 | 0.07, 32.94 | |
Anaplastic thyroid carcinoma (n = 7) | 0/7 | |||||||||||
Mean ± SD | 43.7 ± 11.9 | 1.4 ± 0.3 | 11.4 ± 7.0 | 1.2 ± 0.8 | 1.2 ± 0.7 | 1.1 ± 0.6 | 1.0 ± 0.6 | 12.4 ± 15.6 | 11.8 ± 15.3 | 10.8 ± 13.8 | 10.0 ± 13.5 | |
Median | 41 | 1.3 | 10.1 | 0.88 | 0.75 | 0.71 | 0.69 | 9.5 | 8.2 | 7.7 | 6.96 | |
Range | 23, 60 | 1, 1.8 | 3, 18.1 | 0.1, 2.45 | 0.59, 2.41 | 0.71, 2.17 | 0.49, 2.11 | 0.21, 46.6 | 1.51, 45.8 | 1.2, 41.2 | 1.07, 40.1 | |
P value | 0.284* | 0.207† | 0.404* | 0.074* | 0.642* | 0.609* | 0.545* | 0.485* | 0.479* | 0.516* | 0.433* | 0.403* |
*Kruskal Wallis test, †Pearson chi-square.