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. 2018 Mar 2;9:415. doi: 10.3389/fimmu.2018.00415

Figure 4.

Figure 4

CCR6 C-terminal Ser/Thr clusters differentially regulate CCL-20-induced chemotaxis. (A) Jurkat cells stably expressing wild-type CCR6 (WT-CCR6) or various CCR6 mutants were analyzed by transwell migration assays. The data are expressed as percentage of input cells that migrated to the lower chamber in the absence of CCL20. (B) WT-CCR6 or various CCR6 transfectants were analyzed by transwell migration assays. The data are expressed as percentage of input cells that migrated to the lower chamber containing 50 ng/ml CCL20. Data represent the mean ± SEM from four independent experiments (**p < 0.01 and ***p < 0.001 vs. WT-CCR6).