Skip to main content
. 2018 Mar 2;9:65. doi: 10.3389/fgene.2018.00065

FIGURE 3.

FIGURE 3

CC2D1A and CC2D1B are both involved in object memory. (A) Schematic design of short-term novel object recognition test (NORT), with a novel object replacing a familiar object after a 15 min interval. (B,C) In contrast to WT, 1bKO, and 1a/1bHET male (B) and female (C) mice showed no preference for the novel object relative to a familiar object. Results expressed as mean ± SEM, ∗∗p < 0.01 (two-tailed t-test with equal variance). (D–F) Exploration time divided by initial exploration of training objects 1 and 2 (D), test objects 3 and 4 (E) and total exploration across the two phases of the NORT (F). 1a-1bHET males show a trend toward increased exploration in each test phase which reaches significance when both phases are combined. Results expressed as mean ± SEM, one-way ANOVA with Dunnett’s multiple comparison test, ∗p < 0.05, ∗∗p < 0.01.