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. 2018 Mar 2;9:174. doi: 10.3389/fmicb.2018.00174

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Copyright © 2018 Caspi and Dekker.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Overview of the biological functions of ESCRT and CdvB proteins. (A) In animal cells, ESCRT proteins participate in the last stage of cytokinesis (abscission). (B) In Fungi and Animalia, ESCRT proteins are responsible for cargo sorting into the endosomes and for the biogenesis of multivesicular bodies (MVB). For participation of ESCRT proteins in other biological pathways, see the main text. (C) In Crenarchaeota, the Cdv system participates in (i) cell division, as well as in (ii) viral release and exovesicle secretion.