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. 2018 Mar 2;9:423. doi: 10.3389/fimmu.2018.00423

Table 1.

Importance of performing tissue imaging.

  • Cells in their natural environment

  • Tissue architecture, stromal cells

  • Compartmentalization of immune reactivity (immune cells, soluble factors)

  • Complexity of local immune dynamics

  • Displacement of cells and duration of local interactions

  • Dynamics and mechanisms of virus transmission

  • Generation of new questions

  • Tissue pathology and damage