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. 2018 Mar 2;9:110. doi: 10.3389/fneur.2018.00110

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Copyright © 2018 Wu, Yang, Zhou, Wang, Wang, Hu, He and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Box plots displaying 25, median value, 75 (box), and 95% (whiskers) of cerebral blood flow (CBF) value distributions in the 10 typical regions of interest (ROIs) of healthy control subjects, minimally conscious state (MCS) patients, and vegetative state (VS) patients. Compared with VS patients, the regional mean CBF with post-labeled delay (PLD) 1.5 s for MCS patients had a pattern of relatively decreased CBF in most ROIs, but not significantly. As the PLD changed to 2.5 s, the regional mean CBF for MCS had a pattern of significantly increased CBF in the regions including the putamen, anterior cingulate gyrus, and medial frontal cortex (P < 0.05) (as shown by arrows).