Table 6.
Circulating microRNA profiles according to different atherosclerotic disease locations
| Upregulated | Downregulated | ||
|---|---|---|---|
| Carotid | let-7ζ, miR-21α,β, miR-29aβ, miR-92a, miR-211, miR-218 | miR-30γ, miR-31, miR-125a-5p, miR-126-3pγ,ζ, miR-143, miR-145, miR-221-3pγ, miR-222-3p, miR-320b | |
| Inferior limbs | Whole blood | miR-411 | let 7eδ,ζ, miR-15a, miR-15b, miR-16, miR-20b, miR-25, miR-26b, miR-27bε, miR-28-5p, miR-126γ,ζ, miR-195, miR-196b miR-335, miR-363 |
| Plasma | miR-27bβ,ε, miR-130aβ, miR-210β | miR-18a-5p, miR-27a-3p, miR-30e-5pγ, miR-106a-5p, miR-196b, miR-199a-3p, miR-223-3p, miR-652-3p | |
| Inferior limbs/arteriosclerosis obliterans | miR-21α,β, miR-27bβ,ε, miR-124, miR-130aβ, miR-210β, miR-221-5p, miR-4284, | miR-221-3pγ, miR-432, miR-4463, miR-4306 | |
| Renal artery | miR-126ζ | - |
Upregulated in atherosclerotic disease of different arterial territories;
upregulated in different studies on atherosclerotic disease of the same arterial territory;
downregulated in atherosclerotic disease of different arterial territories;
downregulated in different studies on atherosclerotic disease of the same arterial territory;
opposite trends in different studies on atherosclerotic disease of the same arterial territory;
opposite trends in different studies on atherosclerotic disease of the different arterial territories.