Table 1.
Correlation between two types of anesthesia and clinicopathological features in gastric cancer patients
| Variables | Overall patients
|
Matched patients
|
||||
|---|---|---|---|---|---|---|
| TIVA | INHA | P-value | TIVA | INHA | P-value | |
|
|
|
|||||
| (n=1,506) | (n=1,350) | (n=897) | (n=897) | |||
| Age (years) | 0.174 | 1.000 | ||||
| <60 | 868 (57.6%) | 744 (55.1%) | 516 (57.5%) | 516 (57.5%) | ||
| ≥60 | 638 (42.4%) | 606 (44.9%) | 381 (42.5%) | 381 (42.5%) | ||
| BMI (kg/m2) | 0.099 | 0.708 | ||||
| <20 | 359 (23.8%) | 358 (26.5%) | 235 (26.2%) | 242 (27.0%) | ||
| ≥20 | 1,147 (76.2%) | 992 (73.5%) | 662 (73.8%) | 655 (73.0%) | ||
| Duration of surgery (hours) | 0.593 | 0.962 | ||||
| <3.5 | 825 (54.8%) | 753 (55.8%) | 505 (56.3%) | 504 (56.2%) | ||
| ≥3.5 | 681 (45.2%) | 597 (44.2%) | 392 (43.7%) | 393 (43.8%) | ||
| Gender | 0.083 | 0.951 | ||||
| Female | 1,193 (79.2%) | 1,033 (76.5%) | 738 (82.3%) | 737 (82.2%) | ||
| Male | 313 (20.8%) | 317 (23.5%) | 159 (17.7%) | 160 (17.8%) | ||
| Smoking | 0.131 | 0.925 | ||||
| No | 726 (48.2%) | 689 (51.0%) | 442 (49.3%) | 440 (49.1%) | ||
| Yes | 780 (51.8%) | 661 (49.0%) | 455 (50.7%) | 457 (50.9%) | ||
| Alcoholism | 0.474 | 0.925 | ||||
| No | 810 (53.8%) | 708 (52.4%) | 463 (51.6%) | 465 (51.8%) | ||
| Yes | 696 (46.2%) | 642 (47.6%) | 434 (48.4%) | 432 (48.2%) | ||
| Hypertension | 0.063 | 0.785 | ||||
| No | 1,360 (90.3%) | 1,190 (88.1%) | 830 (92.5%) | 833 (92.9%) | ||
| Yes | 146 (9.7%) | 160 (11.9%) | 67 (7.5%) | 64 (7.1%) | ||
| Ischemic cardiomyopathy | 0.969 | 0.515 | ||||
| No | 1,414 (93.9%) | 1,268 (93.9%) | 864 (96.3%) | 869 (96.9%) | ||
| Yes | 92 (6.1%) | 82 (6.1%) | 33 (3.7%) | 28 (3.1%) | ||
| Diabetes | 0.174 | 0.790 | ||||
| No | 1,438 (95.5%) | 1,274 (94.4%) | 869 (96.9%) | 867 (96.7%) | ||
| Yes | 68 (4.5%) | 76 (5.6%) | 28 (3.1%) | 30 (3.3%) | ||
| ASA | 0.566 | 0.963 | ||||
| I | 204 (13.5%) | 199 (14.7%) | 91 (10.1%) | 89 (9.9%) | ||
| II | 1,197 (79.5%) | 1,065 (78.9%) | 770 (85.8%) | 770 (85.8%) | ||
| III | 105 (7.0%) | 86 (6.4%) | 36 (4.0%) | 38 (4.2%) | ||
| Cancer stage | 0.860 | 0.849 | ||||
| Lower (I–II) | 844 (56.0%) | 761 (56.4%) | 499 (55.6%) | 503 (56.1%) | ||
| Higher (III) | 662 (44.0%) | 589 (43.6%) | 398 (44.4%) | 394 (43.9%) | ||
| Tumor differentiation | 0.632 | 0.919 | ||||
| Lower (1) | 563 (37.4%) | 493 (36.5%) | 283 (31.5%) | 281 (31.3%) | ||
| Higher (2–4) | 943 (62.6%) | 857 (63.5%) | 614 (68.5%) | 616 (68.7%) | ||
Notes: Detected by Pearson’s χ2 tests. Degrees of differentiation: degree 1, poorly differentiated; degree 2, moderately differentiated; degree 3, well differentiated; degree 4, other/unknown differentiated. Cancer stages: stage I: T1, N0, M0/T2, N0, M0/T1, N1, M0; stage II: T3, N0, M0/T4a, N1, M0/T3, N1, M0/T2, N2, M0/T1, N3, M0; stage III: T2, N3, M0/T3, N2, M0/T3, N3, M0/T4a, N2, M0/T4a, N3, M0/any T4b, any N, M0; stage IV: any T, any N, M1.
Abbreviations: ASA, American Society of Anesthesiologists; BMI, body mass index; INHA, inhalational anesthesia; TIVA, total intravenous anesthesia.