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. 2018 Mar 6;9:813. doi: 10.1038/s41467-018-03206-y

Table 1.

Homologous genomic regions differentiating wilds from domestics in Ovis and Capra

Chromosome Code Gene Δπ
Ovis 1 | Capra 3 ENSOARG00000006800 | SLAMF7 Novel gene | SLAM family member 7 0.12 | 0.11
Ovis 1 | Capra 3 SLAMF1 Signaling lymphocytic activation molecule precursor 1 0.13 | 0.10
Ovis 1 | Capra 1 Intergenic None 0.09 | 0.14
Ovis 2 | Capra 2 Intergenic None 0.15 | 0.08
Ovis 3 | Capra 5 KITLG Proto-oncogene receptor tyrosine kinase ligand 0.18 | −0.15
Ovis 3 | Capra 5 KITLG Proto-oncogene receptor tyrosine kinase ligand 0.26 | −0.21
Ovis 3| Capra 5 HMGI-C High mobility group protein I-C 0.11 | 0.12
Ovis 6 | Capra 6 HERC5 | HERC6 HECT & RLD domain containing E3 ubiquitin protein ligase 5 | 6 0.24 | −0.11
Ovis 6 | Capra 6 SLC34A2 | Intergenic Solute carrier family 34 member 2 | None 0.18 | 0.23
Ovis 7 | Capra 10 Intergenic None 0.08 | 0.20
Ovis 9 | Capra 14 POP1 Ribonuclease P/MRP subunit −0.03 | 0.11
Ovis 10 | Capra 12 NBEA Neurobeachin 0.11 | 0.16
Ovis 10 | Capra 12 CRYL1 Crystallin lambda 1 0.01 | 0.19
Ovis 11 | Capra 19 RNF213 Ring finger protein 213 0.13 | −0.26
Ovis 15 | Capra 15 U1 | HBE1 U1 spliceosomal RNA | Hemoglobin subunit epsilon-1 0.22 | 0.09
Ovis 16 | Capra 20 TRIP13 | SLC12A7 Thyroid hormone receptor interactor 13 | Solute carrier family 12 member 7 0.16 | −0.16
Ovis 20 | Capra 23 SUPT3H SPT3 homolog, SAGA and STAGA complex component 0.08 | 0.06
Ovis 20 | Capra 23 EXOC2 | DUSP22 Exocyst complex component 2 | Dual specificity phosphatase 22 0.25 | 0.03
Ovis 24 | Capra 25 HBM | LUC7L Hemoglobin subunit Mu | LUC like 7 0.33 | 0.12
Ovis 26 | Capra 27 MTMR7 Myotubularin related protein 7 0.15 | 0.07

When different in both genera, information is given for Ovis | Capra. Positive Δπ indicates a lower diversity in domestics (e.g., directional positive or stabilizing selection in domestics) while negative values indicate a lower diversity in the wilds (e.g., diversifying selection / relaxation in domestics or recent positive selection in the wilds). The phenotypic effects presented are inferred from the bibliography and classified in a livestock perspective. The Uniprot GO terms associated to these genes are available from Supplementary Data 4