Table 1.
Clinical characteristics of the QUEBEC-CAVS cohort
| Characteristics | Cases (n = 1009) | Controls (n = 1017) |
|---|---|---|
| Age (years) | 72.5 ± 8.4 | 70.9 ± 8.1 |
| Gender (% male) | 63.6 | 64.7 |
| Aortic valve area (cm2) | 0.77 ± 0.30 (19) | NA |
| Mean gradient (mm Hg) | 41.1 ± 16.0 (64) | NA |
| Concomitant coronary artery bypass grafting (%) | 53.3 | 98.3 |
| Diabetes (%) | 32.4 | 32.4 |
| Hypertension (%) | 75.6 | 75.0 |
| BMI (kg/m2) | 28.6 ± 5.4 | 27.7 ± 4.7 |
| Cholesterol (mmol/L) | 4.2 ± 1.1 (30) | 3.9 ± 1.0 (23) |
| Triglycerides (mmol/L) | 1.5 ± 0.9 (32) | 1.5 ± 0.8 (24) |
| LDL-C (mmol/L) | 2.2 ± 0.9 (36) | 2.0 ± 0.8 (31) |
| HDL-C (mmol/L) | 1.3 ± 0.4 (32) | 1.1 ± 0.3 (28) |
| Lipid-lowering treatment (%) | 72.6 | 88.0 |
| eGFR (mL/min/1.73 m2) | 66.9 ± 18.2 (1) | 68.6 ± 16.7 (3) |
Continuous variables are mean ± SD. Number of missing values is shown in parentheses when applicable. eGFR was estimated using the CKD-EPI equation50