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. 2018 Mar 6;9:827. doi: 10.1038/s41467-018-03202-2

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Environmental impacts on gene expression profiles override that of genotype. Contrasting the effects of ancestry and regional environment on differential gene expression. a Between FC-locals (different regional ancestry, different regional environments). b Between FC-locals and FC regional migrants (same regional ancestry, different regional environments). c Between FC-locals and FC regional migrants (different regional ancestries, same regional environment). d Between FC-locals and Europeans (different continental ancestries, same regional environment). Pink dots are genes with FDR (q value) below 5% and red dots are genes with p value < Bonferroni-corrected p value (3.20 × 10⁻⁶)