Table 2.
Comparison of history of vascular risk factors (VRFs) and current medication among DLB, PDD, and AD groups
| n (%) | Odds ratio (95% CI) | |||||
|---|---|---|---|---|---|---|
| DLB | PDD | AD | DLB versus AD | PDD versus AD | PDD versus DLB | |
| History | ||||||
| Hypertension | 33 (60.0) | 16 (47.1) | 51 (65.4) | 0.79 (0.39–1.62) | 0.47 (0.21–1.07) | 0.59 (0.25–1.40) |
| Diabetes | 16 (29.1) | 6 (17.6) | 24 (30.8) | 0.92 (0.43–1.96) | 0.48 (0.18–1.32) | 0.52 (0.18–1.50) |
| Smoking | 22 (40.0) | 8 (25.8) | 23 (29.5) | 1.59 (0.77–3.90) | 0.83 (0.33–2.13) | 0.52 (0.20–1.37) |
| Physical inactivity | 36 (65.5) | 17 (54.8) | 48 (61.5) | 1.18 (0.58–2.43) | 0.76 (0.33–1.76) | 0.64 (0.26–1.58) |
| Hyperlipidemia | 4 (7.3) | 2 (5.9) | 11 (14.1) | 0.48 (0.14–1.59) | 0.38 (0.08–1.82) | 0.80 (0.14–4.60) |
| Atherosclerosis | 2 (3.6) | 2 (5.9) | 9 (11.5) | 0.29 (0.06–1.40) | 0.48 (0.10–2.35) | 1.25 (0.46–3.37) |
| Current medication | ||||||
| Antihypertensive drugs | 22 (40.0) | 15 (44.1) | 37 (47.4) | 0.74 (0.37–1.49) | 0.88 (0.39–1.97) | 1.18 (0.50–1.81) |
| Antidiabetic drugs | 11 (20.0) | 3 (8.8) | 21 (26.9) | 0.68 (0.30–1.55) | 0.26 (0.07–0.95)a | 0.39 (0.10–1.50) |
| Statins | 3 (5.5) | 2 (5.9) | 6 (7.7) | 0.69 (0.17–2.90) | 0.75 (0.14–3.92) | 1.08 (0.17–6.84) |
| Antiplatelet drugs | 16 (29.1) | 7 (20.6) | 17 (21.8) | 1.47 (0.67–3.25) | 0.93 (0.35–2.50) | 0.63 (0.23–1.74) |
| Antiparkinson drugs | 26 (47.3) | 27 (79.4) | 10 (12.8) | 6.10 (2.61–14.25)b | 26.23 (9.05–75.99)b | 4.30 (1.61–11.53)b |
| Antidementia drugs | 5 (9.1) | 10 (29.4) | 19 (24.4) | 0.31 (0.11–0.89)a | 1.29 (0.53–3.19) | 4.17 (1.28–13.54)b |
n, Number of cases; DLB, dementia with Lewy bodies; PDD, Parkinson's disease dementia; AD, Alzheimer's disease.
a
p < .05.
b
p < .005.