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. 2018 Feb 7;8(3):e00929. doi: 10.1002/brb3.929

Table 3.

Treatment with the 5‐HT 2C R antagonist SB243213/5‐HT 2C R inverse agonist SB206553 impacted percentage of Htr2c RNA editing at A and B sites of isolated BALB/c mice in amygdala on statistical analysis

Editing sites C SI C + SB243213 SI + SB243213 C + SB206553 SI + SB206553
A site (%) 83.12 ± 2.10 85.78 ± 1.99* 85.51 ± 2.06 83.03 ± 1.84# 85.68 ± 0.75 82.06 ± 1.31+
B site (%) 67.23 ± 1.32 68.61 ± 2.39* 68.64 ± 3.20 65.32 ± 1.08# 68.06 ± 1.55 63.85 ± 1.32+
D site (%) 48.67 ± 3.91 43.51 ± 10.78 48.27 ± 1.45 47.12 ± 6.32 49.60 ± 2.67 48.37 ± 0.57
C/E site (%) 34.42 ± 3.33 33.38 ± 1.70 32.66 ± 1.16 32.20 ± 1.09 33.47 ± 0.77 31.80 ± 0.85

SI, social isolation.

The data were expressed as the means ± SD.

The above results were analyzed by t test, Post hoc testing of LSD and nonparametric methods. The t test results were *= .297 (C vs. SI), #= .041 (SI vs. SI + SB243213), + = .028 (SI vs. SI + SB206553) at the A site, and *= .250 (C vs. SI), # = .028 (SI vs. SI + SB243213), + = .043 (SI vs. SI + SB206553) at the B site. The hoc testing of LSD analyzed results was obtained as follows: at A site, *= .143 (C vs. SI), # = .055 (SI vs. SI + SB243213), + = .012 (SI vs. SI + SB206553); at B site, *= .299 (C vs. SI), # = .019 (SI vs. SI + SB243213), + = .001 (SI vs. SI + SB206553). The following nonparametric method analyzed results were obtained: at A site, *p = .221 (C vs. SI), # p = .086 (SI vs. SI + SB243213), + p = .027 (SI vs. SI + SB206553); at B site, *p = .327(C vs. SI), # p = .027 (SI vs. SI + SB243213), + p = .014 (SI vs. SI + SB206553) (n = 5/group).