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. 2018 Mar;188(3):768–784. doi: 10.1016/j.ajpath.2017.10.022

Figure 5.

Figure 5

Metanephric mesenchymal (MM) cell proliferation and migration in response to platelet-derived growth factor B chain (PDGF-BB) and vascular endothelial growth factor (VEGF)-A. A: MM cell proliferation is dose dependent in response to 1 to 20 ng/mL PDGF-BB. B: MM cell proliferation peaks at 5 ng/mL VEGF-A. C: MM cell migration is most robust in response to PDGF-BB relative to VEGF-A. Data are expressed as means ± SEM. n = 3 independent experiments. P < 0.05 basal conditions versus each growth factor; P < 0.05 PDGF-BB versus VEGF-A.