Table 2.
Serum Levels of ALT, AST, γ-GT, ALP, Total Cholesterol, Free HDL, and Free LDL and LW/BW Data
| Group | ALT, U/L | AST, U/L | γ-GT, U/L | ALP, U/mL | Free HDL, μg/μL | Free LDL, μg/μL | LW, g | BW, g | LW/BW ratio, g |
|---|---|---|---|---|---|---|---|---|---|
| WT CD | 42.0 ± 12.0 | 273.0 ± 15.58 | 8.0 ± 2.0 | 1.08 ± 0.03 | 2.46 ± 0.24 | 2.25 ± 0.05 | 1.45 ± 0.03 | 27.05 ± 0.44 | 5.36 ± 0.05 |
| WT HFD | 194.0 ± 2.0∗ | 379 ± 24.26∗ | 13.0 ± 1.0 | 1.49 ± 0.11∗ | 1.67 ± 0.04∗ | 1.95 ± 0.02 | 2.0 ± 0.15∗ | 26.43 ± 0.45 | 7.52 ± 0.45∗ |
| Hdc−/− CD | 79.0 ± 2.64 | 225 ± 1.73 | 4.0 ± 2.0 | 1.33 ± 0.03 | 1.63 ± 0.25 | 1.49 ± 0.02 | 1.50 ± 0.03 | 27.71 ± 0.29 | 5.40 ± 0.08 |
| Hdc−/− HFD | 233 ± 1.0∗,† | 417 ± 3.0∗ | 3.0 ± 0.0† | 1.03 ± 0.02† | 2.16 ± 0.02∗,† | 2.21 ± 0.24 | 2.85 ± 0.27 | 34.31 ± 0.81† | 8.29 ± 0.59 |
Data are expressed as means ± SEM.
ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BW, body weight; CD, control diet; γ-GT, γ-glutamyl transferase; HDL, high-density lipoprotein; HFD, high-fat diet; LDL, low-density lipoprotein; LW, liver weight; WT, wild type.
∗
P < 0.05 versus WT CD.
†
P < 0.05 versus WT HFD.