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. 2018 Mar;188(3):757–767. doi: 10.1016/j.ajpath.2017.11.012

Figure 3.

Figure 3

The activation of the IL-17/IL-22 signaling pathways in a hypoxia-ischemia (HI)–induced preterm brain injury mouse model. A and B: The gene expression profile of transcription factors, receptors, signaling adaptors, and cytokines for the IL-17 (A) and IL-22 (B) pathways in the mouse brain after HI-induced preterm brain injury. Data are expressed as means ± SEM of the ratio of the target gene to the reference gene Rna18s1. n = 5 to 6 for uninjured controls; n = 6 to 8 for HI groups. ∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001.