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. 2018 Mar;141(3):1074–1084.e9. doi: 10.1016/j.jaci.2017.04.038

Fig 5.

Fig 5

Effect of Janssen 130 and NAC on generator DEP–induced depolarization of guinea pig vagus nerve. A and B, Trace showing the effect of the TRPA1 antagonist Janssen 130 (10 μmol/L; Fig 5, A) or the antioxidant NAC (1 mmol/L; Fig 5, B) on generator DEP (1 μg/mL)–induced depolarization of the guinea pig vagus nerve. C, Summary graph of effect of vehicle (0.1% DMSO), Janssen 130 (10 μmol/L), and NAC (1 mmol/L) on generator DEP (1 μg/mL)–induced depolarization (n = 3-5). *P < .05, paired t test comparing antagonist responses with control responses in the same tissue. Data are expressed as means ± SEMs.