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. 2018 Feb 1;15(4):4827–4836. doi: 10.3892/ol.2018.7922

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Copyright: © Fu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Visnagin-loaded NP synthesis. (A) Synthesis of NP. NIPAAm and MMA were polymerized with DMAEMA and BPO in an N₂ atmosphere at 70°C. (B) Chemical structure of visnagin. (C) Scanning electron microscopy image of the NP. NP were microspherical in shape and their size was approaching 100 nm. (D) NP-visnagin release curve. NP-visnagin was dissolved in NaH₂PO₄-Na₂HPO₄ solution at 37°C and at each time point, the sample was analyzed with an ultraviolet-visible spectrometer. NP, nanoparticles; NIPA Am, N-isopropylacrylamide; MAA, methacrylic acid; DMAEMA, 2-(dimethylamino) ethyl methacrylate; BPO, Benzoyl peroxide.