Table 2. Definitions of symptoms to exclude active tuberculosis before providing tuberculosis preventive treatment to adults and children living with human immunodeficiency virus (HIV) in countries with the highest burdens of tuberculosis or HIV-associated tuberculosis .

Country	Adults living with HIV			Children living with HIV
	Symptoms defined by WHO	Additional symptoms or findings		Symptoms defined by WHO	Additional symptoms or findings
Angola	Current cough; fever; night sweats; weight loss	N/A		Current cough; fever; weight loss  or poor weight gain	Chest X-ray findings suggestive of tuberculosis
Bangladesh	N/A	N/A		Current cough; fever; contact history with a tuberculosis case; weight loss  or poor weight gain	Fatigue, lethargy, neck mass, wheeze, ascites
Botswana	N/A	N/A		N/A	N/A
Cambodia	Current cough; fever; night sweats	Fatigue; lethargy; wheeze; neck mass; abdominal mass; ascites		Current cough; fever; contact history with a tuberculosis case; weight loss  or poor weight gain	Failure to thrive, enlarged lymph nodes
Cameroon	Current cough; fever; night sweats; weight loss	N/A		Current cough; fever; weight loss  or poor weight gain	N/A
Central African Republic	Current cough; fever; night sweats; weight loss	N/A		Current cough; fever; contact history with a tuberculosis case; weight loss  or poor weight gain	N/A
Democratic Republic of the Congo	Current cough; fever; night sweats; weight loss	N/A		Current cough; fever; contact history with a tuberculosis case; weight loss  or poor weight gain	N/A
Ethiopia	Current cough; fever; night sweats; weight loss	N/A		Current cough; fever; contact history with a tuberculosis case; weight loss  or poor weight gain	N/A
Ghana	N/A	N/A		Current cough; fever; contact history with a tuberculosis case; weight loss  or poor weight gain	Fatigue, lethargy, neck swelling, wheeze
India	Current cough; fever; night sweats; weight loss	N/A		N/A	N/A
Indonesia	Current cough; fever; night sweats; weight loss	Signs of extrapulmonary tuberculosis		N/A	N/A
Kenya	Current cough; fever; night sweats; weight loss	N/A		Current cough; fever; contact history with a tuberculosis case; weight loss  or poor weight gain	Lethargy, less playful than usual
Lesotho	Current cough; fever; night sweats; weight loss	N/A		Current cough; fever; contact history with a tuberculosis case; weight loss  or poor weight gain	N/A
Malawi	Current cough; fever; night sweats; weight loss	N/A		Current cough; fever	Failure to thrive, night sweats, malnutrition
Mozambique	N/A	N/A		Current cough; fever; weight loss  or poor weight gain	N/A
Myanmar	Current cough; fever; night sweats; weight loss	N/A		Current cough; fever; contact history with a tuberculosis case; weight loss  or poor weight gain	N/A
Namibia	Current cough; fever; night sweats; weight loss	Chest pain; shortness of breath; haemoptysis; loss of appetite; diarrhoea; fatigue; enlarged lymph nodes		Current cough; fever; contact history with a tuberculosis case; weight loss  or poor weight gain	Enlarged lymph nodes
Nigeria	Current cough; fever; night sweats; weight loss	N/A		N/A	N/A
Pakistan	Current cough; fever; night sweats; weight loss	N/A		Current cough; fever; contact history with a tuberculosis case; weight loss  or poor weight gain	N/A
Papua New Guinea	Current cough; night sweats; weight loss	N/A		N/A	N/A
Philippines	Current cough; fever; night sweats; weight loss	N/A		N/A	N/A
Sierra Leone	Current cough; fever; night sweats; weight loss	N/A		N/A	N/A
South Africa	Current cough; fever; night sweats; weight loss	N/A		Current cough; fever; contact history with a tuberculosis case; weight loss  or poor weight gain	Fatigue
Swaziland	Current cough; fever; night sweats; weight loss	N/A		Current cough; fever; contact history with a tuberculosis case; weight loss  or poor weight gain	N/A
Thailand	N/A	N/A		N/A	N/A
Uganda	Current cough; fever; night sweats; weight loss	N/A		N/A	N/A
United Republic of Tanzania	Current cough; fever; night sweats; weight loss	N/A		Fever; contact history with a tuberculosis case; weight loss  or poor weight gain	N/A
Viet Nam	Current cough; fever; night sweats; weight loss	N/A		N/A	N/A
Zambia	Current cough; fever; night sweats; weight loss	N/A		Current cough; fever; contact history with a tuberculosis case; weight loss  or poor weight gain	N/A
Zimbabwe	Current cough; fever; night sweats; weight loss	Haemoptysis		N/A	N/A

HIV: human immunodeficiency virus; N/A: data not available; WHO: World Health Organization.

Notes: WHO recommended four-symptom algorithm for people living with HIV includes: current cough, fever, night sweats and weight loss for adults and current cough, fever, poor weight gain and contact history with a tuberculosis case for children.¹⁰