Figure 1.

PD-L1 expression on iDCs and mDCs. iDCs from the peripheral blood of healthy donors and patients with colorectal cancer were obtained. The phenotype of the iDCs was analyzed by flow cytometry. Monocytes isolated from peripheral blood mononuclear cells underwent maturation for 8 days and mDCs were then harvested. The phenotypes of the mDCs were analyzed by flow cytometry. The PD-L1 expression rates on (A) DC1 and (B) DC2 cells were analyzed. *P<0.05 and **P<0.01. iDC, immature dendritic cell; mDC, mature dendritic cell; PD-L1, programmed death-ligand 1.